rhBMP-2ÀÇ ÀÛ¿ë±âÀü°ú ±¸°¾Ç¾È¸é ¿µ¿ªÀÇ °ñÀç»ýÀ» À§ÇÑ rhBMP-2ÀÇ È°¿ë
Bone regeneration in oral and maxillofacial field using rhBMP-2
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¹Ú¹Î¿ì ( Park Min-Woo ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
¹ÚÀçºÀ ( Park Jae-Bong ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
¹ÚÇö¼ö ( Park Hyun-Soo ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
¹é½ÂÁØ ( Paek Seung-Jun ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
¼³Èñ°æ ( Sul Hee-Kyung ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
ÀÌ°æÁø ( Lee Kyung-Jin ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
È«µ¿È¯ ( Hong Dong-Hwan ) - ¼¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°¾Ç¾È¸é¿Ü°úÇб³½Ç
KMID : 0362720150530010028
Abstract
To overcome shortcoming of autogeneous, allogenic, xenogenic and alloplastic bone grafts, various growth factors related to bone regeneration have been identified and developed. Among them, rhBMP-2 is regarded as the most potent osteoinductive growth factor and it can trigger the differentiation of mesenchymal stem cells to osteogenic cells for accelerated new bone formation And several commercial products of rhBMP-2 are available in Korea. It is applied to maxillary sinus augmentation, guided bone regeneration and preservation of extraction socket. In this review, the development, action mechanism and clinical applications of rhBMP-2 will be described.
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rhBMP-2; carrier; alveolar bone; oral and maxillofacial bone regeneration
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